Dr. Reginald V. Fant (“Reggie”) died unexpectedly Sunday, September 27, 2020, following complications of a stroke. He was the Director of Clinical Pharmacology and Abuse Potential Assessment at PinneyAssociates (PA), in Bethesda, Maryland, where he worked for over 23 years. He led many of PA’s abuse potential assessments of medicines in development. Dr. Fant’s efforts contributed to new medicines for treating addiction, anxiety, depression, epilepsy, pain, ADHD, sleep disorders, Parkinson’s Disease, and many more, and involved conventional medicines as well as therapeutic applications of cannabinoids, psychedelics and dietary supplements such as kratom. His work was key in dozens of new drug filings to the FDA and led to more than 75 scientific articles.
Born in Thibodaux, Louisiana, Dr. Fant was awarded his BA in psychology at Nichols State University in 1989. After achieving his PhD in experimental psychology from the University of Southern Mississippi in 1993, he was awarded a post-doctoral fellowship at Johns Hopkins University in the Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, in the School of Medicine under the direction of Professor Maxine Stitzer, along with Professors George Bigelow and Roland Griffiths. This was followed by his recruitment to the Biology of Dependence and Abuse Potential laboratory of the Intramural Research Program of the National Institute on Drug Abuse (NIDA) in 1995, where he worked under the direction of Drs. Jack Henningfield and Wallace Pickworth. In 1997, we welcomed him to PinneyAssociates.
Dr. Fant’s thoughtful and creative approaches to understanding the potential addiction and abuse risks, and potential medical and public health benefits of new medicines so they could be properly regulated based on their potential benefits and risks stood out from the crowd. His contributions helped advance public health both nationally and globally. His work included studies contributing to FDA’s regulation of tobacco and other nicotine delivering products such as cigarette substitutes and medicines for treating tobacco dependence.
His Louisiana roots and family were an important part of his daily life. His passions included weightlifting, gardening and cooking. He was an especially cherished friend and colleague by his extended family at PinneyAssociates and Johns Hopkins. His passing leaves an enormous void at PinneyAssociates, in the field of abuse potential assessment more broadly, and in the hearts of many. We will never forget his warmth and kindness, his sense of humor, or his easy-going spirit. He will be sorely missed.
We share here a link to his obituary.