Jack Henningfield, Ph.D.

Vice President, Research, Health Policy, and Abuse Liability

Jack E. Henningfield is one of the world’s leading experts on addiction, and the behavioral, cognitive, and central nervous system (CNS) effects of drugs. He counsels clients on assessment of the abuse liability of new CNS-acting drugs and formulations, evaluation of potential application of the Controlled Substances Act to new products, assessment of the tamper resistance of novel formulations, and development of risk management approaches.

Jack frequently liaises with the Food and Drug Administration on issues concerning drug scheduling and addiction, and has presented frequently to FDA Advisory Committees. He has contributed to numerous comments to FDA on topics including prescribing of opioids for chronic pain, development and regulation of abuse-deterrent opioid formulations, and regulation of nicotine delivery systems.

Jack’s research has resulted in the writing of numerous books and monographs, and over 400 published papers on myriad topics in public health, pharmacology, and addiction. He has received numerous awards for his research and policy contributions to the understanding and control of tobacco addiction.

He joined PinneyAssociates in September 1996 after 16 years of public service at the Intramural Research Program of the National Institutes of Health’s National Institute on Drug Abuse (NIDA), where he studied the abuse liability and cognitive effects of a broad range of drugs and contributed to the development of improved methods for abuse liability assessment.

At NIDA, he served as Chief of its Human Performance Laboratory (1984-1985), Chief of the Biology of Dependence and Abuse Potential Assessment Section (1985-1996), and Chief of the Clinical Pharmacology Research Branch (1989-1996). He was a frequent contributor to NIDA’s reports to Congress, Reports of the Surgeon General, and contributed to numerous congressional testimonies on behalf of NIDA.

He has been a member of the Johns Hopkins University School of Medicine faculty since 1978 and is presently Adjunct Professor of Behavioral Biology, at the Medical School’s Department of Psychiatry and Behavioral Sciences, and an affiliated faculty with The Johns Hopkins Bloomberg School of Public Health. Jack is also a former faculty member with the Program of Toxicology at the University of Maryland at Baltimore.

A summa cum laude graduate of the University of Minnesota in 1974 with a bachelor’s in psychology, Jack received his doctorate in experimental psychology in 1977 from the University of Minnesota’s Psychopharmacology Training Program, where his focus was addiction, CNS medications, preclinical abuse liability assessment, and drug addiction control. Jack’s post-doctoral training included roles as a National Council on Alcoholism postdoctoral research fellow at the University of Minnesota from 1977-1978 and at the Johns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit. He was a staff fellow at the NIDA Addiction Research Center from 1980-1982.